A middle-aged Mediterranean woman presents for her initial patient visit at a dermatology clinic through which you are rotating. Her physical exam is remarkable for small vesicles as well as large bullae, some of which have ruptured to leave weeping, crusted, inflamed patches on her trunk, face, neck, and scalp. Notably, her extremities are spared. You recognize the disease, which is caused by an autoimmune antibody attack on the intercellular cement that binds epidermis. What is your diagnosis?
A. Epidermolysis bullosa
C. Bullous pemphigoid
D. Dermatitis herpetiformis
A 36-year-old African American male with a past medical history significant for AIDS presents to the clinic concerned about an intensely pruritic rash present on the webs of his fingers and toes, as well as his wrists. A physical exam demonstrates burrows so small they are barely visible to the naked eye. What agent is responsible for his “rash?”